Celiac disease is an intestinal disease that affects one to two per cent of Norway’s population. Hereditary factors play a role in the development of the disease. For reasons we do not fully understand, people with a hereditary susceptibility can experience an immune response to gluten proteins that are present in wheat, barley and rye.
The immune system misinterprets gluten as part of a dangerous infection. The immune system attacks the intestinal epithelium and produces antibodies against both gluten and an enzyme produced in the body called transglutaminase.
Celiac disease patients suffer from many different complaints, such as diarrhoea, stomach pains and poor nutrient absorption. Many of these symptoms are due to the damage the immune system inflicts on the body. The disease can be treated with a strict gluten-free diet.
Celiac disease is strongly under-diagnosed in Norway, and it has been estimated that there are 20–30,000 undiagnosed celiac disease sufferers.
Knut E. A. Lundin
Gastroenterology. Professor University of Oslo and Oslo University Hospital.
Immunology. Assosiate professor University of Oslo.
Geir Kjetil Sandve
Bioinformatics. Assosiate professor, University of Oslo.
Ludvig M. Sollid (centre leader)
Immunology. Professor at University of Oslo and Oslo University Hospital.
Genetics. Professor ved Department of Genetics, University Medical Center Groningen, Nederland.
Professor, University of Oslo and Oslo University Hospital
Tom Hemming Karlsen
Professor, University of Oslo and Oslo University Hospital.
Researcher, University of Oslo.
Geir Åge Løset
Research leader, Nextera AS, Oslo, Norway.
K. G. Jebsen Coeliac Disease Research Centre
University of Oslo, Rikshospitalet
Department of Immunology
P.O.Box 4950 Nydalen
Professor Paul Klenerman, Oxford University, England
Professor Markku Mäki, Tampere University, Finland
Professor Vivianne Malmström, Karolinska Institutet, Sweden
Dr. Heidi Urwin, Research leader, Coeliac UK
Knut H. Peterson, leader, Norwegian Coeliac Assosiation
Virusfunn gir håp om en kur mot cøliaki (New virus-findings gives hope for a cure for coeliac disease)
Dagens medisin, 26.8.2016:
Åpnet nytt senter for cøliakiforskning (Opening of a new centre for research on coeliac disease)
Universitetet i Oslo, 18.8.2016:
Åpning av senter for cøliakiforskning (Opening of a centre for coeliac disease)