{"id":5441,"date":"2022-05-04T13:38:21","date_gmt":"2022-05-04T11:38:21","guid":{"rendered":"http:\/\/stiftkgj.webforslag.com\/senter\/k-g-jebsen-senter-for-tromboseforskning-trec\/"},"modified":"2023-06-27T10:23:43","modified_gmt":"2023-06-27T08:23:43","slug":"k-g-jebsen-thrombosis-research-and-expertise-center-trec","status":"publish","type":"senter","link":"https:\/\/stiftkgj.no\/en\/senter\/k-g-jebsen-thrombosis-research-and-expertise-center-trec\/","title":{"rendered":"K. G. Jebsen Thrombosis Research and Expertise Center (TREC)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css=&#8221;.vc_custom_1651580050061{margin-right: 0px !important;margin-left: 0px !important;background-image: url(https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/04\/Topp-bilde-2.jpg?id=427) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column]<div class=\"spacer-5830a5ea62c1f2880975a2ceab4a96be2\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 767px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 979px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 400px;}}@media (min-width: 1200px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 400px;}}<\/style>[\/vc_column][\/vc_row][vc_row el_class=&#8221;article-white&#8221; css=&#8221;.vc_custom_1649536549777{margin-right: 0px !important;margin-left: 0px !important;}&#8221;][vc_column][vc_row_inner][vc_column_inner]<div class=\"spacer-f96c97828f0d47b1724343c705ecae9d423\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 767px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 979px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 1200px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}<\/style><div class=\"header left  \"><h1 class=\"font-size-sm\" title=\"K. G. Jebsen Thrombosis Research and Expertise Center (TREC)\" style=\"color:#0054a2\">K. G. Jebsen Thrombosis Research and Expertise Center (TREC)<\/h1><\/div>[\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;3\/4&#8243;][vc_video link=&#8221;https:\/\/player.vimeo.com\/video\/217562017&#8243;][vc_column_text]Our research will lead to more targeted preventive measures and better treatment for those affected by this disease. We will also be able to reduce the number of cases and deaths.<\/p>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>The goal of the KG Jebsen Thrombosis Research and Expertise Center (TREC) is to identify risk factors for, and expand our understanding of, venous thrombosis.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>In Europe, around 540,000 deaths per year are related to venous thrombosis. By comparison, around 68,000 people die of breast cancer in the same region. Of patients who suffer a blood clot in the leg, 20 to 50 per cent subsequently have problems with pain and swelling as a result of reduced circulation. At the same time, society incurs high costs relating to treatment and possible loss of income because some patients are unable to work after suffering a venous thrombosis.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p><a href=\"https:\/\/uit.no\/om\/enhet\/ansatte\/person?p_document_id=41807&amp;p_dimension_id=88116\" target=\"_blank\" rel=\"noopener\">Professor John-Bjarne Hansen<\/a> received support in 2014 from the K G Jebsen Foundation, UiT Arctic University of Norway and the Northern Norway regional health authority to establish G Jebsen TREC \u2013 Thrombosis Research and Expertise Center.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p><strong>Our research focus<\/strong><strong><br \/>\n<\/strong>The point of departure for our research is that venous thrombosis is a common disease with an unclear and complicated development for which the risk factors are only partly known.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>There are four areas relating to venous thrombosis that we study at TREC: genetic variants, regulators of gene expression (miRNAs), circulating microparticles (that stem from activated or dying blood cells) and specific proteins in the blood.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>We carry out experimental studies in model systems in order to uncover the disease\u2019s underlying mechanisms. In addition, we are investigating whether the connection between arterial and venous thrombosis is due to common risk factors or whether it is due to one of the diseases directly affecting the other.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p><strong>Risk factors<\/strong><strong><br \/>\n<\/strong>Researchers have previously uncovered some risk factors that can lead to a blood clot. Several factors have yet to be identified, however, and we still do not know enough about how the known factors interact.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>Studies of families and twins have shown that there is a significant genetic component. We already know some of the genetic risk factors , but they can only explain a fraction of the blood clots that have to do with heredity. The interplay between genetics and some environmental factors can further increase the risk of a blood clot. This is another thing about which we still know far too little, however.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>To find the most important genes that increase the risk of a blood clot, we are investigating 250 genes and 200,000 gene variants in 6,000 persons, half of whom have had venous thrombosis. An earlier study showed promising results in terms of discovering new genetic risk factors for venous thrombosis.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>Population surveys such as\u00a0<a href=\"https:\/\/uit.no\/om\/enhet\/artikkel?p_document_id=70715&amp;p_dimension_id=88111\" target=\"_blank\" rel=\"noopener\">the Troms\u00f8 survey<\/a>,\u00a0<a href=\"https:\/\/www.ntnu.no\/hunt\" target=\"_blank\" rel=\"noopener\">the Nord-Tr\u00f8ndelag health study<\/a>, and similar surveys from Denmark and the Netherlands are part of the research material.<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p><strong>Cooperation<\/strong><strong><br \/>\n<\/strong>We are more than 30 people working in TREC in Troms\u00f8. Our studies will take place both here and, with the help of our partners, in Bod\u00f8, Oslo, the Netherlands and the USA. We are therefore participating in an international network of researchers with specialised expertise. They will complement each other, thus enabling us to achieve the goal for the centre<\/p>\n<\/div>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>KG Jebsen TREC is funded by the KG Jebsen Foundation, Northern Norway regional health authority and UIT Arctic University of Norway. The centre was the first KG Jensen centre for medical research to be established in Northern Norway.<\/p>\n<\/div>\n<\/div>\n<p>[\/vc_column_text]<div class=\"header left  \"><span class=\"font-size-xxs\" title=\"Group leaders\" >Group leaders<\/span><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Hansen, John-Bjarne\" style=\"color:#0054a2\">Hansen, John-Bjarne<\/span><div class=\"subheader\"><p>Professor, University of Troms\u00f8<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Arshad, Nadia\" style=\"color:#0054a2\">Arshad, Nadia<\/span><div class=\"subheader\"><p>PhD-student, University of Troms\u00f8.<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Sigrid Br\u00e6kkan\" style=\"color:#0054a2\">Sigrid Br\u00e6kkan<\/span><div class=\"subheader\"><p>Assosiate professor, University of Troms\u00f8.<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Trond B\u00f8rvik\" style=\"color:#0054a2\">Trond B\u00f8rvik<\/span><div class=\"subheader\"><p>University of Troms\u00f8.<\/p><\/div><\/div><div class=\"header left  \"><h2 class=\"font-size-sm\" title=\"Mediaomtale\" >Mediaomtale<\/h2><\/div><div class=\"external-links-container light-blue\"><ul class=\"external-links\"><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/uit.no\/forskning\/forskningsgrupper\/nyheter?p_document_id=374322\" target=\"_blank\" rel=\"noopener\">Universitetet i Troms\u00f8:<\/a><span class=\"description\">Nyheter hentet fra senterets webside<\/span><\/li><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/unikard.org\/kan-hjerte-og-karrisiko-avslores-presist-med-gamle-enkeltmalinger\/\" target=\"_blank\" rel=\"noopener\">Unikard (Nasjonal satsing p\u00e5 hjerte- og karforskning)<\/a><span class=\"description\">Kan hjerte- og karrisiko avsl\u00f8res presist med gamle enkeltm\u00e5linger?<\/span><span class=\"date\">21.12.2016<\/span><\/li><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/www.itromso.no\/nyheter\/i\/m1Xr4E\/hjort-jeg-er-heldig-som-lever\" target=\"_blank\" rel=\"noopener\">ITroms\u00f8<\/a><span class=\"description\">Hjort: jeg her heldig som lever<\/span><span class=\"date\">21.6.2014<\/span><\/li><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/uit.no\/nyheter\/artikkel?p_document_id=381091&amp;p_dim=\" target=\"_blank\" rel=\"noopener\">Universitetet i Troms\u00f8<\/a><span class=\"description\">Blodproppforskning av internasjonal klasse fikk eget senter ved UiT<\/span><span class=\"date\">21.7.2014<\/span><\/li><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/www.nordlys.no\/nyheter\/dette-rammer-10-000-personer-i-aret\/s\/1-79-7430827\" target=\"_blank\" rel=\"noopener\">Nordlys<\/a><span class=\"description\">Dette rammer 10 000 personer i \u00e5ret<\/span><span class=\"date\">20.6.2014<\/span><\/li><\/ul><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"infobox light-brown\"><h3>The centre in brief<\/h3>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>Leader: John-Bjarne Hansen<br \/>\nStartup: 2014<br \/>\nHost institution: University of Troms\u00f8<br \/>\nFunding: 16 + 9 MNOK<br \/>\nHome page:\u00a0<a href=\"https:\/\/uit.no\/forskning\/forskningsgrupper\/gruppe?p_document_id=374322\" target=\"_blank\" rel=\"noopener noreferrer\">K. G. Jebsen TREC<\/a>, the centre\u2019s\u00a0<a href=\"https:\/\/www.facebook.com\/KGJebsenTREC\/\" target=\"_blank\" rel=\"noopener\">facbook<\/a>\u00a0page, the centre\u2019s\u00a0<a href=\"https:\/\/twitter.com\/TREC_UiT\" target=\"_blank\" rel=\"noopener\">twitter<\/a><\/p>\n<\/div>\n<\/div>\n<\/div><div class=\"infobox light-brown\"><h3>Contact information<\/h3>\n<div class=\"width-container\">\n<p><strong>Visiting address:<\/strong><\/p>\n<\/div>\n<div class=\"width-container\">Farmasibygget;Farmasiloftet 4 etg.<br \/>\nRom F4.210<\/div>\n<div class=\"width-container\">\n<p><strong>Postal address:<\/strong><\/p>\n<\/div>\n<div class=\"width-container\">K.G. Jebsen TREC<\/div>\n<div class=\"width-container\">Det helsevitenskapelige\u00a0fakultet<br \/>\nUiT Norges arktiske universitet<br \/>\n9037 Troms\u00f8<\/div>\n<\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"spacer-19ba46bd32479517faefa95d8bc53e873425752342356\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 767px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 979px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}@media (min-width: 1200px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}<\/style>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Our research will lead to more targeted preventive measures and better treatment for those affected by this disease. We will also be able to reduce the number of cases and deaths. [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary vidiflex-read-more-link\" href=\"https:\/\/stiftkgj.no\/en\/senter\/k-g-jebsen-thrombosis-research-and-expertise-center-trec\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"featured_media":488,"template":"","categories":[39],"class_list":["post-5441","senter","type-senter","status-publish","has-post-thumbnail","hentry","category-medical-research-old"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter\/5441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter"}],"about":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/types\/senter"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media\/488"}],"wp:attachment":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media?parent=5441"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/categories?post=5441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}