{"id":5629,"date":"2022-08-23T20:01:55","date_gmt":"2022-08-23T18:01:55","guid":{"rendered":"http:\/\/stiftkgj.webforslag.com\/?post_type=senter&#038;p=5629"},"modified":"2026-03-12T15:04:32","modified_gmt":"2026-03-12T14:04:32","slug":"k-g-jebsen-centre-for-cardiac-biomarkers","status":"publish","type":"senter","link":"https:\/\/stiftkgj.no\/en\/senter\/k-g-jebsen-centre-for-cardiac-biomarkers\/","title":{"rendered":"K.G. Jebsen Centre for Cardiac Biomarkers"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css=&#8221;.vc_custom_1651580050061{margin-right: 0px !important;margin-left: 0px !important;background-image: url(https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/04\/Topp-bilde-2.jpg?id=427) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column]<div class=\"spacer-5830a5ea62c1f2880975a2ceab4a96be2\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 767px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 979px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 300px;}}@media (min-width: 1200px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 300px;}}<\/style>[\/vc_column][\/vc_row][vc_row el_class=&#8221;article-white&#8221; css=&#8221;.vc_custom_1649536549777{margin-right: 0px !important;margin-left: 0px !important;}&#8221;][vc_column][vc_separator color=&#8221;chino&#8221; border_width=&#8221;2&#8243;][vc_row_inner][vc_column_inner]<div class=\"header left  \"><h1 class=\"font-size-sm\" title=\"K.G. Jebsen Centre for Cardiac Biomarkers\" style=\"color:#0054a2\">K.G. Jebsen Centre for Cardiac Biomarkers<\/h1><\/div>[\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;3\/4&#8243;]\n\t\t\t<figure  class=\"standard-image left no-caption\">\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"563\" src=\"https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM.jpg\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM.jpg 1000w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-300x169.jpg 300w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-768x432.jpg 768w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-320x180.jpg 320w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-420x236.jpg 420w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-576x324.jpg 576w, https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/12\/Omland-OH-1000x562_DM-992x558.jpg 992w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/>\n\t\t\t\t\n\t\t\t<\/figure>[vc_column_text css=&#8221;&#8221;]<em>The K.G. Jebsen Centre for Cardiac Biomarkers seeks to answer critical unanswered questions in cardiovascular medicine. The Centre&#8217;s goal is to improve understanding of disease mechanisms that cause heart damage and heart failure through studies of established and new biomarkers associated with heart disease, which will lead to better prevention and treatment of these conditions.\u00a0<\/em><\/p>\n<p><span data-contrast=\"auto\">The centre aims to identify new methods for assessing the risk of future disease and improve the prognosis for patients with established disease by combining laboratory research with patient centered research and data derived from large population studies.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In the Western world, cardiovascular disease is one of the leading causes of morbidity and mortality. Approximately one-fifth of the Norwegian population lives with or is at high risk of developing cardiovascular disease, and there is an urgent need for new diagnostic methods. We also need more information to forecast how the disease will progress and how effective treatment will be.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Circulating biomarkers are substances found in the blood that reflect disease severity, prognosis, and treatment response. Biomarker analyses will be performed in blood samples collected in large population studies such as the Health Survey in Tr<\/span><span data-contrast=\"auto\">\u00f8<\/span><span data-contrast=\"auto\">ndelag (HUNT) and the Akershus Cardiac Examination (ACE) 1950 study to discover new cardiac markers and disease mechanisms for heart damage. Established biomarkers, such as the heart muscle protein troponin, as well as new biomarkers, will be studied.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The blood contains thousands of different proteins. While it was previously common to analyze only one or a few biomarkers at a time, new methodology, known as proteomics, now allows the analysis of thousands of biomarkers in a small blood sample volume. Proteomics analyses not only help to identify disease earlier and more precisely, but also provide unique insight into the disease process itself. Attack points for future heart failure treatment can thus be identified. <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Certain cancer treatments have been linked to an increased risk of heart damage. Cancer can also increase the likelihood of heart damage. However, it is unclear whether the cancer treatment or the cancer itself is more likely to cause heart damage and heart failure. Initiated by investigators in the Centre, participants in the large HUNT survey had heart biomarker measurements performed, which can be used to detect early signs of heart damage and subsequent risk of heart failure. By comparing this information to data from health registers, we can gain a better understanding of the relationship between cancer, cancer treatment, and heart damage. The Centre will also test new treatment strategies in order to prevent heart damage after cancer treatment.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The Centre will also investigate the link between genetic factors and the risk of scar tissue formation in the heart, a condition known as cardiac fibrosis. Fibrosis is one of the most important pathophysiological changes in a failing heart and has a bearing on prognosis.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The Centre will collaborate closely with leading international heart disease research groups, its own international scientific advisory panel, and its own user panel of patients with established heart and vascular disease, as well as Norwegian business in biotechnology research and innovation.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The Centre, which is anchored at the Department of Clinical Medicine at the University of Oslo and is led by Professor Torbj<\/span><span data-contrast=\"auto\">\u00f8<\/span><span data-contrast=\"auto\">rn Omland, was established on September 1, 2022, as the first located at Akershus University Hospital.<\/span><\/p>\n<p>The K.G. Jebsen Centre for Cardiac biomarkers is funded by the Foundation K.G. Jebsen, the University of Oslo and Akershus University Hospital.[\/vc_column_text]<div class=\"header left  \"><h2 class=\"font-size-sm\" title=\"The centre in the media\" >The centre in the media<\/h2><\/div><div class=\"external-links-container light-blue\"><ul class=\"external-links\"><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/www.med.uio.no\/klinmed\/english\/about\/news-and-events\/news\/2022\/opening-of-the-k.g.-jebsen-centre-for-cardiac-biomarkers.html\" target=\"_blank\" rel=\"noopener\">University of Oslo<\/a><span class=\"description\">Opening of the K.G. Jebsen Centre for Cardiac Biomarkers<\/span><span class=\"date\">01.03.2022<\/span><\/li><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/www.med.uio.no\/klinmed\/english\/about\/news-and-events\/news\/2022\/new-jebsen-centre-for-cardiac-research.html\" target=\"_blank\" rel=\"noopener\">University of Oslo<\/a><span class=\"description\">New Jebsen Centre for Cardiac Research<\/span><span class=\"date\">01.03.2022<\/span><\/li><\/ul><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"infobox light-brown\"><h3>Facts about the Centre<\/h3>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p id=\"hdr\">Leader: Torbj\u00f8rn Omland<br \/>\nCentre period: 2022 \u2013 2028<br \/>\nHost institution: University of Oslo<br \/>\nFunding: 22,5 MNOK<\/p>\n<\/div>\n<style>\na {<br \/>    text-decoration: none;<br \/>    color: #464feb;<br \/>}<br \/>tr th, tr td {<br \/>    border: 1px solid #e6e6e6;<br \/>}<br \/>tr th {<br \/>    background-color: #f5f5f5;<br \/>}<br \/><\/style>\n<div>\n<p>Centre period: 2022 \u2013 2027<br \/>\nHost institution: University of Oslo<br \/>\nAllocation: 22.5 MNOK<\/p>\n<p><strong>Centre Management:<\/strong><\/p>\n<p><strong>Torbj\u00f8rn Omland<\/strong><br \/>\nCentre Director, Professor I, University of Oslo<\/p>\n<p><strong>Helge R. R\u00f8sj\u00f8<\/strong><br \/>\nDeputy Director, Professor II, University of Oslo<\/p>\n<p><strong>Work Package Leaders:<\/strong><\/p>\n<p><strong>Magnus N. Lyngbakken<\/strong><br \/>\nProfessor II, University of Oslo<\/p>\n<p><strong>Peder L. Myhre<\/strong><br \/>\nProfessor I, University of Oslo<\/p>\n<p><strong>Ida G. Lunde<\/strong><br \/>\nProfessor II, University of Oslo<\/p>\n<p><strong>Siri L. Heck<\/strong><br \/>\nAssociate Professor, University of Oslo<\/p>\n<p><strong>Coordinator:<\/strong><\/p>\n<p><strong>Victoria Vinje-Jakobsen<\/strong><br \/>\nPhD Candidate and Senior Executive Officer, University of Oslo<\/p>\n<\/div>\n<\/div>\n<\/div><div class=\"infobox light-brown\"><h3>Contact information<\/h3>\n<div class=\"width-container\">\n<p><strong>K. G. Jebsen Centre for Cardiac Biomarkers<\/strong><\/p>\n<p><strong>Visiting Address:<br \/>\n<\/strong>Akershus University Hospital<\/p>\n<\/div>\n<\/div>[vc_single_image image=&#8221;6040&#8243; img_size=&#8221;medium&#8221;]<div class=\"infobox grey\"><h3><\/h3><p>From the left:\u00a0 Siri Lagethon Heck, Peder Langeland Myhre, Ida Gjervold Lunde, Helge R\u00f8rvik R\u00f8sj\u00f8, Torbj\u00f8rn Omland, Sveinung Hole (former CEO Stiftelsen Kristian Gerhard Jebsen), Magnus Nakrem Lyngbakken, Stener Kvinnsland, Anett Helleb\u00f8 Ottesen. Photo: Anne Wikdahl Haga, Ahus.<\/p><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"spacer-19ba46bd32479517faefa95d8bc53e873425752342356\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 767px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 979px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}@media (min-width: 1200px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}<\/style>[\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>K.G. Jebsen Center for Cardiac Biomarkers aims to answer important unsolved questions in cardiac medicine. [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary vidiflex-read-more-link\" href=\"https:\/\/stiftkgj.no\/en\/senter\/k-g-jebsen-centre-for-cardiac-biomarkers\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"featured_media":6036,"template":"","categories":[32],"class_list":["post-5629","senter","type-senter","status-publish","has-post-thumbnail","hentry","category-medical-research"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter\/5629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter"}],"about":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/types\/senter"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media\/6036"}],"wp:attachment":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media?parent=5629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/categories?post=5629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}