{"id":7085,"date":"2026-05-15T15:13:17","date_gmt":"2026-05-15T13:13:17","guid":{"rendered":"https:\/\/stiftkgj.no\/?post_type=senter&#038;p=7085"},"modified":"2026-05-22T11:56:35","modified_gmt":"2026-05-22T09:56:35","slug":"kg-jebsen-center-for-specific-autoimmune-therapy","status":"publish","type":"senter","link":"https:\/\/stiftkgj.no\/en\/senter\/kg-jebsen-center-for-specific-autoimmune-therapy\/","title":{"rendered":"K. G. Jebsen Center for Specific Autoimmune Therapy"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css=&#8221;.vc_custom_1651580050061{margin-right: 0px !important;margin-left: 0px !important;background-image: url(https:\/\/stiftkgj.no\/wp-content\/uploads\/2022\/04\/Topp-bilde-2.jpg?id=427) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221;][vc_column]<div class=\"spacer-5830a5ea62c1f2880975a2ceab4a96be2\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 767px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 200px;}}@media (min-width: 979px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 400px;}}@media (min-width: 1200px) { .spacer-5830a5ea62c1f2880975a2ceab4a96be2{ height: 400px;}}<\/style>[\/vc_column][\/vc_row][vc_row el_class=&#8221;article-white&#8221; css=&#8221;.vc_custom_1649536549777{margin-right: 0px !important;margin-left: 0px !important;}&#8221;][vc_column][vc_row_inner][vc_column_inner]<div class=\"spacer-f96c97828f0d47b1724343c705ecae9d423\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 767px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 979px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}@media (min-width: 1200px) { .spacer-f96c97828f0d47b1724343c705ecae9d423{ height: 10px;}}<\/style><div class=\"header left  \"><h1 class=\"font-size-sm\" title=\"K. G. Jebsen Center for Specific Autoimmune Therapy\" style=\"color:#0054a2\">K. G. Jebsen Center for Specific Autoimmune Therapy<\/h1><\/div>[\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;3\/4&#8243;][vc_single_image image=&#8221;7086&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<div id=\"KnM9nf\" class=\"PZPZlf\" data-attrid=\"tw-sourceArea\" data-entityname=\"Google Translate\">\n<div id=\"tw-container\" class=\"nev7se\" data-cp=\"1\" data-nnttsvi=\"1\" data-sletp=\"false\" data-sm=\"1\" data-ssbp=\"false\" data-sugg-time=\"500\" data-sugg-url=\"https:\/\/clients1.google.com\/complete\/search\" data-uilc=\"no\" data-vil=\",af,af-ZA,am,am-ET,ar-EG,ar-AE,ar-KW,ar-QA,ar,ar-IL,ar-JO,ar-LB,ar-PS,az,az-AZ,bg,bg-BG,bn,bn-BD,bn-IN,ca,ca-es,cs,cs-CZ,de,de-DE,de-CH,de-AT,de-LI,en,en-US,en-CA,en-AU,en-NZ,en-GB,en-IN,en-KE,en-TZ,en-NG,en-GH,en-PH,en-ZA,es,es-ES,es-AR,es-UY,es-419,es-BO,es-CL,es-CR,es-CO,es-DO,es-EC,es-GT,es-HN,es-NI,es-PA,es-PE,es-PR,es-PY,es-SV,es-VE,es-MX,es-US,eu,eu-ES,fi,fi-FI,fr,fr-FR,fr-CH,fr-BE,gl,gl-ES,gu,gu-IN,he,he-IL,iw,iw-IL,hu,hu-HU,hy,hy-AM,id,id-ID,is,is-IS,it,it-IT,it-CH,ja,ja-JP,jv,jv-ID,ka,ka-GE,km,km-KH,kn,kn-IN,ko,ko-KR,la,lo,lo-LA,lv,lv-LV,ml,ml-IN,mr,mr-IN,ms,ms-MY,nl,nl-NL,nb,nb-NO,ne,ne-NP,pl,pl-PL,pt,pt-BR,pt-PT,ro,ro-RO,ru,ru-RU,si-LK,sk,sk-SK,sr,sr-RS,su,su-ID,sv,sv-SE,sw,sw-TZ,sw-KE,ta,ta-IN,ta-SG,ta-LK,ta-MY,te,te-IN,tr,tr-TR,ur,ur-PK,ur-IN,yue,yue-HK,yue-Hant-HK,zh-HK,zh,zh-CN,zh-cmn,zh-cmn-CN,zh-Hans,zh-Hans-CN,zh-cmn-Hans,zh-cmn-Hans-CN,cmn-CN,cmn-Hans,cmn-Hans-CN,zh-TW,zh-Hant-TW,cmn-TW,cmn-Hant-TW,zh-cmn-TW,zh-cmn-Hant-TW,zu,zu-ZA,hi,hi-IN,tl,tl-PH,pa,pa-IN\">\n<div id=\"tw-ob\" class=\"tw-src-ltr\">\n<div class=\"oSioSc\">\n<div id=\"tw-target\">\n<div id=\"kAz1tf\" class=\"g9WsWb PZPZlf\" data-attrid=\"tw-targetArea\" data-entityname=\"Google Translate\">\n<div id=\"tw-target-text-container\" class=\"tw-ta-container tw-nfl\" tabindex=\"0\" role=\"text\">\n<div id=\"tw-container\" class=\"nev7se\" data-cp=\"1\" data-nnttsvi=\"1\" data-sletp=\"false\" data-ssbp=\"false\" data-sugg-time=\"500\" data-sugg-url=\"https:\/\/clients1.google.com\/complete\/search\" data-uilc=\"no\" data-vil=\",af,af-ZA,am,am-ET,ar-EG,ar-AE,ar-KW,ar-QA,ar,ar-IL,ar-JO,ar-LB,ar-PS,az,az-AZ,bg,bg-BG,bn,bn-BD,bn-IN,ca,ca-es,cs,cs-CZ,de,de-DE,de-CH,de-AT,de-LI,en,en-US,en-CA,en-AU,en-NZ,en-GB,en-IN,en-KE,en-TZ,en-NG,en-GH,en-PH,en-ZA,es,es-ES,es-AR,es-UY,es-419,es-BO,es-CL,es-CR,es-CO,es-DO,es-EC,es-GT,es-HN,es-NI,es-PA,es-PE,es-PR,es-PY,es-SV,es-VE,es-MX,es-US,eu,eu-ES,fi,fi-FI,fr,fr-FR,fr-CH,fr-BE,gl,gl-ES,gu,gu-IN,he,he-IL,iw,iw-IL,hu,hu-HU,hy,hy-AM,id,id-ID,is,is-IS,it,it-IT,it-CH,ja,ja-JP,jv,jv-ID,ka,ka-GE,km,km-KH,kn,kn-IN,ko,ko-KR,la,lo,lo-LA,lv,lv-LV,ml,ml-IN,mr,mr-IN,ms,ms-MY,nl,nl-NL,nb,nb-NO,ne,ne-NP,pl,pl-PL,pt,pt-BR,pt-PT,ro,ro-RO,ru,ru-RU,si-LK,sk,sk-SK,sr,sr-RS,su,su-ID,sv,sv-SE,sw,sw-TZ,sw-KE,ta,ta-IN,ta-SG,ta-LK,ta-MY,te,te-IN,tr,tr-TR,ur,ur-PK,ur-IN,yue,yue-HK,yue-Hant-HK,zh-HK,zh,zh-CN,zh-cmn,zh-cmn-CN,zh-Hans,zh-Hans-CN,zh-cmn-Hans,zh-cmn-Hans-CN,cmn-CN,cmn-Hans,cmn-Hans-CN,zh-TW,zh-Hant-TW,cmn-TW,cmn-Hant-TW,zh-cmn-TW,zh-cmn-Hant-TW,zu,zu-ZA,hi,hi-IN,tl,tl-PH,pa,pa-IN\">\n<div id=\"tw-ob\" class=\"tw-src-ltr\">\n<div class=\"oSioSc\">\n<div id=\"tw-target\">\n<div id=\"kAz1tf\" class=\"g9WsWb PZPZlf\" data-attrid=\"tw-targetArea\" data-entityname=\"Google Translate\">\n<div id=\"tw-target-text-container\" class=\"tw-ta-container tw-nfl\" tabindex=\"0\" role=\"text\">\n<p id=\"tw-target-text\" class=\"tw-data-text tw-text-large tw-ta\" dir=\"ltr\" tabindex=\"-1\" role=\"text\" data-placeholder=\"Oversettelse\" data-ved=\"2ahUKEwiF2IOUzcyUAxUxGxAIHb6SG-kQ3ewLegQIDRAV\" aria-label=\"Oversatt tekst: The primary goal of the KG Jebsen Center for Specific Autoimmune Therapy is to establish approaches that enable specific reduction of the B cells that cause disease. The secondary goal of the center is to establish a powerhouse where clinicians and laboratory scientists interact daily, and which will facilitate the development of the knowledge and skills needed to establish, test, and critically evaluate new advanced therapeutic drugs for patients with autoimmune diseases.\"><strong><span class=\"Y2IQFc\" lang=\"en\">The primary goal of the KG Jebsen Center for Specific Autoimmune Therapy is to establish approaches that enable specific reduction of the B cells that cause disease. The secondary goal of the center is to establish a powerhouse where clinicians and laboratory scientists interact daily, and which will facilitate the development of the knowledge and skills needed to establish, test, and critically evaluate new advanced therapeutic drugs for patients with autoimmune diseases.<\/span><\/strong><\/p>\n<\/div>\n<div id=\"tw-target-rmn-container\" class=\"tw-target-rmn tw-ta-container tw-nfl\" tabindex=\"-1\" role=\"text\">\n<p id=\"tw-target-rmn\" class=\"tw-data-placeholder tw-text-small tw-ta\" dir=\"ltr\" tabindex=\"-1\" role=\"text\"><span style=\"font-family: Georgia, 'Times New Roman', 'Bitstream Charter', Times, serif;\">B cells are a type of white blood cell that is crucial to the immune system. The cells are best known for making antibodies, but they also have an important function in interacting with T cells, another type of white blood cell. These two cell types work together to fight viruses and bacteria. People with autoimmune diseases have a defect in their immune system that causes it to attack its own cells and tissues, as if some cells in the body were a virus. It has been shown that removing all the B cells in the body can be an effective way to treat autoimmune diseases. By using a type of treatment developed for cancer therapy on patients with very severe autoimmune disease, the autoimmune attack on one&#8217;s own tissue has stopped and the disease in these patients has apparently been cured. One type of such treatment is specially made (i.e. genetically modified) T cells (CAR-T cells) that can track down and remove all B cells. Another way is to add molecules (so-called BiTE) to the body that allow normal T cells to remove all B cells. Promising results have also been achieved in animal experiments and in laboratory models using such treatment reagents with the aim of removing only the B cells that cause the disease. In such treatment, surgical warfare is carried out instead of carpet bombing. This has so far only been shown for autoimmune diseases where the molecules (autoantigens) the immune system attacks are on the surface of the body&#8217;s cells. For many autoimmune diseases, the autoantigens are inside the cells. In the preparation of reagents that remove B cells targeting autoantigens inside the cells, there is a cell biology problem. At the K.G. Jebsen Center for Specific Immunotherapy, we want to solve this problem so that we can create new types of advanced immunotherapy that will find and remove the B cells that are involved in the autoimmune attack in diseases where the autoantigens are found inside the cells. We will work with this approach within four autoimmune diseases: systemic sclerosis, antisynthetase syndrome, rheumatoid arthritis and celiac disease.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"tw-container\" class=\"nev7se\" data-cp=\"1\" data-nnttsvi=\"1\" data-sletp=\"false\" data-ssbp=\"false\" data-sugg-time=\"500\" data-sugg-url=\"https:\/\/clients1.google.com\/complete\/search\" data-uilc=\"no\" data-vil=\",af,af-ZA,am,am-ET,ar-EG,ar-AE,ar-KW,ar-QA,ar,ar-IL,ar-JO,ar-LB,ar-PS,az,az-AZ,bg,bg-BG,bn,bn-BD,bn-IN,ca,ca-es,cs,cs-CZ,de,de-DE,de-CH,de-AT,de-LI,en,en-US,en-CA,en-AU,en-NZ,en-GB,en-IN,en-KE,en-TZ,en-NG,en-GH,en-PH,en-ZA,es,es-ES,es-AR,es-UY,es-419,es-BO,es-CL,es-CR,es-CO,es-DO,es-EC,es-GT,es-HN,es-NI,es-PA,es-PE,es-PR,es-PY,es-SV,es-VE,es-MX,es-US,eu,eu-ES,fi,fi-FI,fr,fr-FR,fr-CH,fr-BE,gl,gl-ES,gu,gu-IN,he,he-IL,iw,iw-IL,hu,hu-HU,hy,hy-AM,id,id-ID,is,is-IS,it,it-IT,it-CH,ja,ja-JP,jv,jv-ID,ka,ka-GE,km,km-KH,kn,kn-IN,ko,ko-KR,la,lo,lo-LA,lv,lv-LV,ml,ml-IN,mr,mr-IN,ms,ms-MY,nl,nl-NL,nb,nb-NO,ne,ne-NP,pl,pl-PL,pt,pt-BR,pt-PT,ro,ro-RO,ru,ru-RU,si-LK,sk,sk-SK,sr,sr-RS,su,su-ID,sv,sv-SE,sw,sw-TZ,sw-KE,ta,ta-IN,ta-SG,ta-LK,ta-MY,te,te-IN,tr,tr-TR,ur,ur-PK,ur-IN,yue,yue-HK,yue-Hant-HK,zh-HK,zh,zh-CN,zh-cmn,zh-cmn-CN,zh-Hans,zh-Hans-CN,zh-cmn-Hans,zh-cmn-Hans-CN,cmn-CN,cmn-Hans,cmn-Hans-CN,zh-TW,zh-Hant-TW,cmn-TW,cmn-Hant-TW,zh-cmn-TW,zh-cmn-Hant-TW,zu,zu-ZA,hi,hi-IN,tl,tl-PH,pa,pa-IN\">\n<div id=\"tw-ob\" class=\"tw-src-ltr\">\n<div class=\"oSioSc\">\n<div id=\"tw-target\">\n<div id=\"kAz1tf\" class=\"g9WsWb PZPZlf\" data-attrid=\"tw-targetArea\" data-entityname=\"Google Translate\">\n<div id=\"tw-target-rmn-container\" class=\"tw-target-rmn tw-ta-container tw-nfl\" tabindex=\"-1\" role=\"text\">\n<pre id=\"tw-target-rmn\" class=\"tw-data-placeholder tw-text-small tw-ta\" dir=\"ltr\" tabindex=\"-1\" role=\"text\" data-placeholder=\"\"><\/pre>\n<\/div>\n<div class=\"iYB33c\">\n<div id=\"tw-tmenu\" class=\"tw-menu\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"tw-images\"><\/div>\n<div class=\"dURPtb\"><\/div>\n<div>\n<div data-vpload=\"nYCnEd\" data-v=\"\" data-ne=\"1\">\n<div id=\"tsuid_miQQaoWjCLG2wPAPvqXuyA4_55\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"KFFQ0c xKf9F\"><\/div>\n<\/div>\n<p>[\/vc_column_text]<div class=\"header left  \"><span class=\"font-size-xxs\" title=\"Group leaders\" >Group leaders<\/span><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Rasmus Iversen\" style=\"color:#0054a2\">Rasmus Iversen<\/span><div class=\"subheader\"><p>Immunologist and researcher at Oslo University Hospital (100%)<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Guro L\u00f8vik Goll\" style=\"color:#0054a2\">Guro L\u00f8vik Goll<\/span><div class=\"subheader\"><p>Rheumatologist and senior physician at Diakonhjemmet Hospital (50%), senior researcher (50%) and associate professor at the University of Oslo<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Johanne Tracey Jacobsen\" style=\"color:#0054a2\">Johanne Tracey Jacobsen<\/span><div class=\"subheader\"><p>Immunologist and associate professor at the University of Oslo (100%)<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Knut E. A. Lundin\" style=\"color:#0054a2\">Knut E. A. Lundin<\/span><div class=\"subheader\"><p>Gastroenterologist, internist and professor\/senior physician at the University of Oslo (100%)\/Oslo University Hospital (20%).<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"\u00d8yvind Molberg\" style=\"color:#0054a2\">\u00d8yvind Molberg<\/span><div class=\"subheader\"><p>Rheumatologist. Professor at the University of Oslo (50%), physician and research leader at Oslo University Hospital (70%)<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Marthe T. M\u00e6hlen\" style=\"color:#0054a2\">Marthe T. M\u00e6hlen<\/span><div class=\"subheader\"><p>Rheumatologist\/senior physician\u00a0 (50%) and postdoc (50%) at Oslo University Hospital<\/p><\/div><\/div><div class=\"header left  \"><span class=\"font-size-xss\" title=\"Ludvig M. Sollid (center leader)\" style=\"color:#0054a2\">Ludvig M. Sollid (center leader)<\/span><div class=\"subheader\"><p>Immunologist and professor\/senior physician at the University of Oslo (100%)\/Oslo University Hospital (20%).<\/p><\/div><\/div><div class=\"header left  \"><h2 class=\"font-size-sm\" title=\"Media\" >Media<\/h2><\/div><div class=\"external-links-container light-blue\"><ul class=\"external-links\"><li class=\"inner-item\"><i class=\"fa fa-external-link\"><\/i><a href=\"https:\/\/www.khrono.no\/75-millioner-kroner-til-tre-nye-forskningssentre\/1030812\" target=\"_blank\" rel=\"noopener\">Krhono<\/a><span class=\"description\">75 millioner kroner til tre nye forskningssentre<\/span><span class=\"date\">21.01.2026<\/span><\/li><\/ul><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;]<div class=\"infobox light-brown\"><h3>The Centre in brief<\/h3>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p id=\"hdr\">Leader: Ludvig M. Sollid<br \/>\nStart year: 2026<br \/>\nHost institution: University of\u00a0 Oslo<br \/>\nFunding from the foundation: 25 MNOK<br \/>\nHome page:\u00a0 &#8211; will come soon-<\/p>\n<\/div>\n<\/div>\n<\/div><div class=\"infobox light-brown\"><h3>Contact information:<\/h3><p>KG Jebsen Center for Specific Autoimmune Therapy<br \/>\nUniversitetet i Oslo<br \/>\nInstitutt for klinisk medisin<br \/>\nP.O.Box 4950 Nydalen<br \/>\n0424 Oslo<br \/>\nNorway<\/p><\/div><div class=\"infobox light-brown\"><h3>Scientific advisory board<\/h3>\n<ul>\n<li>Professor Gabriel Victora, Rockefeller University<\/li>\n<li>Professor Rene Toes, Leiden University Medical Center<\/li>\n<li>Professor Vivianne Malmstr\u00f6m, Karolinska Institutet<\/li>\n<\/ul>\n<\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"spacer-19ba46bd32479517faefa95d8bc53e873425752342356\" style=\"\"><\/div><style>@media (min-width: 320px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 767px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 30px;}}@media (min-width: 979px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}@media (min-width: 1200px) { .spacer-19ba46bd32479517faefa95d8bc53e873425752342356{ height: 60px;}}<\/style>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The primary goal of the KG Jebsen Center for Specific Autoimmune Therapy is to establish approaches that enable specific reduction of the B cells that cause disease.<br \/>\nThe center is lead by Ludvig M. Sollid, professor at UiO and senior consultant at OUS [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary vidiflex-read-more-link\" href=\"https:\/\/stiftkgj.no\/en\/senter\/kg-jebsen-center-for-specific-autoimmune-therapy\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"featured_media":7087,"template":"","categories":[32],"class_list":["post-7085","senter","type-senter","status-publish","has-post-thumbnail","hentry","category-medical-research"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter\/7085","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/senter"}],"about":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/types\/senter"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media\/7087"}],"wp:attachment":[{"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/media?parent=7085"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stiftkgj.no\/en\/wp-json\/wp\/v2\/categories?post=7085"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}