K.G. Jebsen Center for Genome-Directed Therapy in Cancer

Foto: UiB

Although there have been great advances in cancer treatment over the recent years, metastatic spread of cancer is in most cases still an incurable disease  

However, in recent years, major technological advances have been made within the field of genetic analyzes. This makes it possible to study the molecular mechanisms that cause cellular proliferation, as well as treatment resistance. Such analyzes will fundamentally change the way we diagnose and treat cancer patients, and also give us the opportunity for much more personalized therapy.

At K.G. Jebsen Center for Genome-Directed Therapy in Cancer, we will conduct new clinical trials on several different cancer forms. This will be done in order to investigate how changes in the cancer genome affect sensitivity to treatment and how cancer therapy should be designed to exploit the genetic defects present in cancer cells. In particular, we will focus on breast cancer, colon cancer, sarcoma, lung cancer and bladder cancer as well as prostate and head&neck cancer. The aim is to find better methods for identifying which patients may benefit from specific therapies but also, in a long term perspective, to develop more effective therapies that can lead to healing of many patients we cannot cure today


Center leadership:

Per Eystein Lønning, will head the Centre, with co-PIs Molecular Biology PI Stian Knappskog (PhD, Senior Research Fellow) and Breast Cancer PI Hans Petter Eikesdal (senior consultant oncologist and professor) acting as deputy leaders.

Group leaders:

Group 1: Molecular biology PI Stian Knappskog (UiB, HUH)

Group 2: Sarcoma group PIs Ola Myklebost

Group 3: Pathology. PI Hrvoje Miletic

Group 4: Breast cancer: PI Hans Petter Eikesdal

Group 5: Colorectal cancer: PI Inger Marie Løes

Group 6: Lung cancer/basket trial: PI Inger Marie Sandvik

About the center:

Leader: Professor Per Eystein Lønning
Start up: 2018
Host institution: University of Bergen
Funding: 18 MNOK

Contact information:

K.G. Jebsen Center for Genome-Directed Therapy in Cancer

Postal address: Universitetet i Bergen, Postboks 7804, 5020 Bergen, Norway

Visiting address: Laboratoriebygget, Jonas Lies veg 87, floor: 1M

E-mail: linn.iversen@uib.no

Administrativ coordinator:
Linn Iversen

Phone: +47 55 97 20 90


Scientific advisory board:

Dr. David Wedge, Group leader, Big Data Institute, University of Oxford, UK

Dr. Mårten Fernø, Senior researcher, Dept. of Oncology and Pathology, University of Lund, Sweden

Dr. Line Bjørge, Professor and group leader, Dept. of Gynecology, Haukeland University Hospital, and Dept. of Clinical Science, University of Bergen, Norway

Patient advisory council:

Hildborg Mandiussen, Representing The Norwegian Breast Cancer Society in Bergen

Ester-Johanne Sande, Representing The Norwegian Cancer Society in Region West

News from Stiftelsen Kristian Gerhard Jebsen

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